Unique ID issued by UMIN | UMIN000040990 |
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Receipt number | R000046801 |
Scientific Title | Evaluation of clinical usefulness of a novel pancreatic cancer marker |
Date of disclosure of the study information | 2020/07/06 |
Last modified on | 2020/07/02 20:28:53 |
Evaluation of clinical usefulness of a novel pancreatic cancer marker
Evaluation of clinical usefulness of a novel pancreatic cancer marker
Evaluation of clinical usefulness of a novel pancreatic cancer marker
Evaluation of clinical usefulness of a novel pancreatic cancer marker
Japan |
Pancreatic cancer
Hepato-biliary-pancreatic medicine | Hepato-biliary-pancreatic surgery |
Malignancy
NO
To evaluate the clinical diagnostic performance of tissue factor pathway inhibitor-2 (TFPI2) in preoperative prediction of pancreatic cancer.
Efficacy
To evaluate the clinical diagnostic performance of TFPI2 in patients with pancreatic cancer (diagnostic accuracy, sensitivity, sensitivity, ROC curve analysis, area under the ROC curve)
To evaluate the complementarity between TFPI2 and conventional markers (CEA, CA19-9, DUPAN-2, SPAN-1). To investigate relation between TFPI2 and thrombosis (D-dimer or imge findings).
Observational
20 | years-old | <= |
Not applicable |
Male and Female
1. Patients with pancreatic disease (inflammation, benign or malignant) who are admitted to Yokohama City University Hospital within the study period and judged to be suitable for this study.
2. Patients planed to undergo surgery (including trial laparotomy) or chemo (radiation) therapy as initial treatments (including patients who do not require therapeutic intervention for inflammatory and benign diseases).
3. Written informed consent.
4. Age over 20.
1.Patients with simultaneous or metachronous double cancer.
2.Samples taken from patients who is considered inappropriate for the inclusion by the responsible physician of each institution.
3. Patients who are pregnant or may be pregnant at the time of blood collection.
100
1st name | Itaru |
Middle name | |
Last name | Endo |
Yokohama City University Graduate School of Medicine
Department of Gastroenterological Surgery
236-0004
3-9 Fukuura, Kanazawa-ku, Yokohama City, 236-0004, Japan
045-787-2800
endoit@med.yokohama-cu.ac.jp
1st name | Yasuhiro |
Middle name | |
Last name | Shimizu |
Yokohama City University Graduate School of Medicine
Department of Gastroenterological Surgery
236-0004
3-9 Fukuura, Kanazawa-ku, Yokohama City, 236-0004, Japan
045-787-2800
yshimizu@yokohama-cu.ac.jp
Yokohama City University
TOSOH CORPORATION
Profit organization
Yokohama City University
3-9 Fukuura Kanazawa-Ku Yokohama
045-370-7627
rinri@yokohama-cu.ac.jp
NO
2020 | Year | 07 | Month | 06 | Day |
Unpublished
Enrolling by invitation
2020 | Year | 01 | Month | 14 | Day |
2020 | Year | 01 | Month | 14 | Day |
2020 | Year | 07 | Month | 06 | Day |
2025 | Year | 03 | Month | 31 | Day |
Analysis of changes in TFPI2 before and after treatment (chemotherapy, surgery)
2020 | Year | 07 | Month | 02 | Day |
2020 | Year | 07 | Month | 02 | Day |
Value
https://center6.umin.ac.jp/cgi-open-bin/ctr_e/ctr_view.cgi?recptno=R000046801
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