Unique ID issued by UMIN | UMIN000041311 |
---|---|
Receipt number | R000047169 |
Scientific Title | Organization of medical knowledge by intelligence science |
Date of disclosure of the study information | 2020/08/06 |
Last modified on | 2024/01/10 10:12:22 |
Organization of medical knowledge by intelligence science
Omniscience-01
Organization of medical knowledge by intelligence science
Omniscience-01
Japan |
Advanced Solid Malignancies
Hematology and clinical oncology |
Malignancy
YES
Identify the usefulness of QA Commons in generating treatment recommendations based on genetic variants and clinical information detected by gene panel testing
Others
usability
1.Agreement rate of evidence Level between the draft QA Commons report and EP
2.Agreement rate of drug reachability between the draft QA Commons report and EP
3.Agreement rate of Secondary Findings between the draft QA Commons report and EP
a.Association of cancer gene panel test results with clinicopathological factors and clinical course
b.Differences in expert panel prep time with and without QA Commons
c.Satisfaction of Annotators on Expert Panels
Observational
20 | years-old | <= |
Not applicable |
Male and Female
Eligibility criteria are cases that meet all of the following 1.) to 3.) criteria to be considered eligible cases.
1,) Diagnosed with a solid malignancy.
2,) Be at least 20 years old.
3,) fall under a. or b. below.
a. Cohort A (Retrospective cohort)
Consent to the FoundationOne CDx Cancer Genome Profile at the National Cancer Institute East Hospital between June 2019 and February 2021, with insurance coverage.
b. Cohort B (Prospective cohort)
Consent to the FoundationOne CDx Cancer Genome Profile at the National Cancer Center East Hospital on or after March 2021, with written consent to participate in this study.
The exclusion criteria were cases that were deemed inappropriate for enrollment in this study by the attending physician.
600
1st name | yoshiaki |
Middle name | |
Last name | nakamura |
National Cancer Center Hospital East
Translational Research Management Division, Clinical Research Support Office
Translational Research Support Section
277-8577
6-5-1, Kashiwanoha, Kashiwa, Chiba
04-7133-1111
yoshinak@east.ncc.go.jp
1st name | takao |
Middle name | |
Last name | fujisawa |
National Cancer Center Hospital East
Head and neck medical oncology
277-8577
6-5-1, Kashiwanoha, Kashiwa, Chiba
04-7133-1111
tafujisa@east.ncc.go.jp
National Cancer Center Hospital East
Genomedia inc.
Profit organization
National Cancer Center Research Ethics Review Committee
5-1-1 Tsukiji, Chuo, Tokyo
03-3542-2511
NCC_IRBoffice@ml.res.ncc.go.jp
NO
2020 | Year | 08 | Month | 06 | Day |
Unpublished
Enrolling by invitation
2020 | Year | 08 | Month | 04 | Day |
2020 | Year | 10 | Month | 12 | Day |
2020 | Year | 10 | Month | 12 | Day |
2024 | Year | 03 | Month | 31 | Day |
Research design: Observational study
Eligibility: Patients with FoundationOne CDx Cancer Genome Profiles performed by insurance
2020 | Year | 08 | Month | 04 | Day |
2024 | Year | 01 | Month | 10 | Day |
Value
https://center6.umin.ac.jp/cgi-open-bin/ctr_e/ctr_view.cgi?recptno=R000047169
Research Plan | |
---|---|
Registered date | File name |
Research case data specifications | |
---|---|
Registered date | File name |
Research case data | |
---|---|
Registered date | File name |