Unique ID issued by UMIN | UMIN000041413 |
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Receipt number | R000047282 |
Scientific Title | Exploratory Study on Companion/Complimentary Diagnosis Platforms for Immune Checkpoint Inhibitor Treatment of Urothelial Cancer Based on Plasma Cell-free DNA |
Date of disclosure of the study information | 2020/09/01 |
Last modified on | 2023/02/03 00:54:20 |
Exploratory Study on Companion/Complimentary Diagnosis Platforms for Immune Checkpoint Inhibitor Treatment of Urothelial Cancer Based on Plasma Cell-free DNA
cfDNA diagnostics for urothelial cancer
Exploratory Study on Companion/Complimentary Diagnosis Platforms for Immune Checkpoint Inhibitor Treatment of Urothelial Cancer Based on Plasma Cell-free DNA
cfDNA diagnostics for urothelial cancer
Japan |
Urothelial cancer
Urology |
Malignancy
YES
Preliminary analysis and feasibility verification of for the development of cfDNA-based platforms focused on the concordance with gene mutation profile, TMB, gene expression profile, immunohistological findings obtained from urothelial cancer tissue.
Others
Observational study
Concordance index of tumor somatic mutation profile based on cfDNA sequence for gene mutation profile, TMB, gene expression profile, immunohistological findings based on tumor tissue.
Predictive values of tumor somatic mutation profile based on cfDNA sequence for patient prognosis and treatment response.
Observational
Not applicable |
Not applicable |
Male and Female
Urothelial cancer patients who have consented to the secondary use of specimens and have both tumor tissue and blood specimens preserved since 2018.
Those who did not give a consent for the secondary use of the sample. Those who opted out the refusal to participate this research.
48
1st name | Takashi |
Middle name | |
Last name | Kobayashi |
Kyoto University Graduate School of Medicine
Department of Urology
606-8507
54 Shogoinkawahara-cho, Sakyo-ku, Kyoto, Japan
075-751-3326
selecao@kuhp.kyoto-u.ac.jp
1st name | Takashi |
Middle name | |
Last name | Kobayashi |
Kyoto University Graduate School of Medicine
Department of Urology
606-8507
54 Shogoinkawahara-cho, Sakyo-ku, Kyoto, Japan
075-751-3326
selecao@kuhp.kyoto-u.ac.jp
Kyoto University Graduate School of Medicine
Chugai Pharmaceutical Co., Ltd.
Profit organization
Kyoto University Graduate School and Faculty of Medicine, Ethics Committee
Yoshidakonoe-cho, Sakyo-ku, Kyoto, Japan
075-753-4680
ethcom@kuhp.kyoto-u.ac.jp
NO
2020 | Year | 09 | Month | 01 | Day |
Unpublished
No longer recruiting
2020 | Year | 07 | Month | 23 | Day |
2020 | Year | 10 | Month | 26 | Day |
2020 | Year | 09 | Month | 01 | Day |
2022 | Year | 06 | Month | 30 | Day |
Observational study on cfDNA-based diagnostics in urothelial carcinoma
2020 | Year | 08 | Month | 14 | Day |
2023 | Year | 02 | Month | 03 | Day |
Value
https://center6.umin.ac.jp/cgi-open-bin/ctr_e/ctr_view.cgi?recptno=R000047282
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