Unique ID issued by UMIN | UMIN000041606 |
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Receipt number | R000047489 |
Scientific Title | Gut microbiome of patients with autism spectrum disordersand attention deficit/hyperactivity disorders: A cross sectional study |
Date of disclosure of the study information | 2020/08/31 |
Last modified on | 2022/01/08 17:40:46 |
Gut microbiome of patients with autism spectrum disordersand attention deficit/hyperactivity disorders: A cross sectional study
Gut microbiome of patients with ASD and ADHD (GMAA study)
Gut microbiome of patients with autism spectrum disordersand attention deficit/hyperactivity disorders: A cross sectional study
Gut microbiome of patients with ASD and ADHD (GMAA study)
Japan |
Autism Spectrum Disorders: ASD Attention Deficit/Hyperactivity Disorders: ADHD
Gastroenterology | Psychiatry |
Others
NO
We collect feces samples from patients with autism spectrum disorders (ASD) and attention deficit/hyperactivity disorders (ADHD), and healthy controls (HCs). Clinical information will also be collected with severity of each disease, lifestyle habits, and gastrointestinal symptoms .
The purpose of this study is to investigate the difference between intestinal bacterial flora and its metabolites in each group and to examine the relationship between intestinal bacterial flora and neuropsychiatric function.
Others
Gut microbiota profiles assessed by 16SrRNA and its metabolites by performing mass spectrometry.
Exploratory
Gut microbiota profiles assessed by 16SrRNA and its metabolites by performing mass spectrometry.
・Original questionnaire of lifestyles
・Brief-type self-administered Diet History Questionnaire: BDHQ
・Autism-spectrum quotient: AQ-J
・Conners' Adult ADHD Rating Scales: CAARS
・Social Functioning Scale: SFS
・Adolescent / Adult Sensory Profile: AASP
・Japanese Adult Reading Test: JART
・Pittsburgh Sleep Quality Index: PSQI
・Gastrointestinal Symptom Rating Scale: GSRS
・Original questionnaire of Gastro-intestinal Symptom
Others,meta-analysis etc
20 | years-old | <= |
50 | years-old | >= |
Male and Female
<Patients with autism spectrum disorders: ASD or attention deficit/hyperactivity disorders: ADHD>
・Age between 20 and 50 at the time of agreement.
・Patients with ASD or ADHD admitted to the Showa University Karasuyama Hospital or the Keio University Hospital.
<Healthy participants>
・People who are willing to participate in this study without the history of psychiatric disorders.
・Age between 20 and 50 at the time of agreement.
・Participants with dementia.
・Participants with gastrointestinal disorder.
・Participants who are receiving the antibiotic treatment.
・Participants who can not agree with collecting faces samples.
100
1st name | Kenji |
Middle name | |
Last name | Sanada |
Showa University School of Medicine
Department of Psychiatry
157-8577
6-11-11Kitakarasuyama Setagaya-ku, Tokyo, Japan
03-3300-5232
ksanappu@gmail.com
1st name | Tomoyuki |
Middle name | |
Last name | Tachibana |
Showa University School of Medicine
Department of Psychiatry
157-8577
6-11-11Kitakarasuyama Setagaya-ku, Tokyo, Japan
03-3300-5232
tachibanat@showa-u.med.ac.jp
Showa University School of Medicine
Department of Psychiatry
None
Self funding
Keio University School of Medicine
Department of Nueropsychiatry
Institute for Advanced Biosciences, Keio University
lnstitutional Review Board of ShowaUniversity Karasuyama Hospital
6-11-11Kitakarasuyama Setagaya-ku, Tokyo, Japan
03-3300-5247
scri@ofc.showa-u.ac.jp
NO
昭和大学附属烏山病院(東京都)
慶應義塾大学病院(東京都)
慶應義塾大学先端生命科学研究所(山形県)
2020 | Year | 08 | Month | 31 | Day |
Unpublished
Preinitiation
2020 | Year | 08 | Month | 17 | Day |
2020 | Year | 08 | Month | 21 | Day |
2020 | Year | 08 | Month | 31 | Day |
2025 | Year | 03 | Month | 31 | Day |
We collect feces samples from patients with autism spectrum disorders (ASD) and attention deficit/hyperactivity disorders (ADHD), and healthy controls (HCs). Clinical information will also be collected with severity of each disease, lifestyle habits, and gastrointestinal symptoms .
The purpose of this study is to investigate the difference between intestinal bacterial flora and its metabolites in each group and to examine the relationship between intestinal bacterial flora and neuropsychiatric function.
2020 | Year | 08 | Month | 29 | Day |
2022 | Year | 01 | Month | 08 | Day |
Value
https://center6.umin.ac.jp/cgi-open-bin/ctr_e/ctr_view.cgi?recptno=R000047489
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