Unique ID issued by UMIN | UMIN000041675 |
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Receipt number | R000047526 |
Scientific Title | The effect of grape-derived pomace extract supplementation on oral periodontal disease-related bacteria |
Date of disclosure of the study information | 2020/10/05 |
Last modified on | 2021/02/16 23:53:02 |
The effect of grape-derived pomace on improving oral environment
Grape pomace and oral environment
The effect of grape-derived pomace extract supplementation on oral periodontal disease-related bacteria
Grape pomace extract trial on periodontal disease-related bacteria
Japan |
Nothing
Adult |
Others
NO
To evaluate the effect of grape-derived pomace extract supplementation on preventing the increase of periodontal disease-related bacteria.
Efficacy
The ocnsentration of P. gingivalis in saliva
Interventional
Parallel
Randomized
Individual
Double blind -all involved are blinded
Placebo
YES
2
Prevention
Food |
Participants consume 1 tablet including 27 mg oleanolic acid every day before night sleeping.
Participants consume 1 placebo tablet not including oleanolic acid every day before night sleeping.
20 | years-old | <= |
80 | years-old | > |
Male and Female
(1) 20 years old or over, and less than 80 years.
(2) 20 % or over in Bleeding of Probing(BOP)
(4) Applicants who understand well the purpose and contents of this trial. Additionally, who can agree to participate by his/her will.
(1) Having allergy against grape or starch
(2) Pregnant of breath feeding
(3) Who need medical treatment for periodontal disease.
(4) Participated in another clinical trial within 3 month.
(5) Who used antibiotics within 2 weeks
(6) Smoker
(7) Others who are judged to be ineligible by the dentist.
50
1st name | Tetsu |
Middle name | |
Last name | Kinoshita |
Institute of Community Life Sciences Co., Ltd.
Social Epidemiology Institute
791-0243
1383-2 Hiraimachi, Matsuyama-city, Ehime
089-904-7811
tetsu.prospective@gmail.com
1st name | Tetsu |
Middle name | |
Last name | Kinoshita |
Institute of Community Life Sciences Co., Ltd.
Social Epidemiology Institute
791-0243
1383-2 Hiraimachi, Matsuyama-city, Ehime
089-904-7811
tetsu.prospective@gmail.com
Institute of Community Life Sciences Co., Ltd.
NIPPON FLOUR MILLS CO., LTD.
Profit organization
Ehime University Hospital Institutional Review Board
Shitsukawa, Toon, Ehime
089-960-5172
rinri@m.ehime-u.ac.jp
NO
2020 | Year | 10 | Month | 05 | Day |
Unpublished
Completed
2020 | Year | 09 | Month | 28 | Day |
2020 | Year | 09 | Month | 28 | Day |
2020 | Year | 09 | Month | 29 | Day |
2020 | Year | 11 | Month | 30 | Day |
2021 | Year | 03 | Month | 31 | Day |
2020 | Year | 09 | Month | 03 | Day |
2021 | Year | 02 | Month | 16 | Day |
Value
https://center6.umin.ac.jp/cgi-open-bin/ctr_e/ctr_view.cgi?recptno=R000047526
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