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UMIN-CTR Clinical Trial |
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Name: | UMIN ID: |
Recruitment status | Open public recruiting |
Unique ID issued by UMIN | UMIN000041956 |
Receipt No. | R000047888 |
Scientific Title | Relation between salivary alpha-amylase and mental stress in patients with Parkinson's disease |
Date of disclosure of the study information | 2020/10/01 |
Last modified on | 2020/09/30 |
Basic information | ||
Public title | Clinical significance of salivary alpha-amylase activity in patients with Parkinson's disease | |
Acronym | Alpha-amylase activity in patients with Parkinson's disease | |
Scientific Title | Relation between salivary alpha-amylase and mental stress in patients with Parkinson's disease | |
Scientific Title:Acronym | Salivary alpha-amylase and mental stress in patients with Parkinson's disease | |
Region |
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Condition | ||
Condition | Parkinson's desease | |
Classification by specialty |
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Classification by malignancy | Others | |
Genomic information | NO |
Objectives | |
Narrative objectives1 | Although salivary alpha amylase has been reported to be associated with psychological stress in the general population, the details are unknown in patients with neurodegenerative diseases. In the present study, we examined the relation between salivary alpha amylase and psychological stress in patients with Parkinson's disease, which is frequently associated with sympathetic neuropathy. |
Basic objectives2 | Bio-availability |
Basic objectives -Others | |
Trial characteristics_1 | |
Trial characteristics_2 | |
Developmental phase |
Assessment | |
Primary outcomes | Correlation of Salivary Alpha-Amylase Activity and Numerical Rating Scale (NRS) |
Key secondary outcomes | Correlation of salivary alpha-amylase activity with age and salivary alpha-amylase activity with orthostatic hypotension |
Base | |
Study type | Observational |
Study design | |
Basic design | |
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Stratification | |
Dynamic allocation | |
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Blocking | |
Concealment |
Intervention | |
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Eligibility | ||||
Age-lower limit |
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Gender | Male and Female | |||
Key inclusion criteria | Parkinson's desease and nomal control | |||
Key exclusion criteria | Unwillingness to participate in the study | |||
Target sample size | 700 |
Research contact person | |||||||
Name of lead principal investigator |
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Organization | Tokushima National Hospital National Hospital Organization | ||||||
Division name | Shikoku Neuromuscular Centre | ||||||
Zip code | 776-0031 | ||||||
Address | 1354 Shikiji, Kamojima, Yoshinogawa, Tokushima | ||||||
TEL | 0883242161 | ||||||
mukaiyama.yui.cr@mail.hosp.go.jp |
Public contact | |||||||
Name of contact person |
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Organization | Tokushima National Hospital National Hospital Organization | ||||||
Division name | Shikoku Neuromuscular Centre | ||||||
Zip code | 776-0031 | ||||||
Address | 1354 Shikiji, Kamojima, Yoshinogawa, Tokushima | ||||||
TEL | 0883242161 | ||||||
Homepage URL | |||||||
mukaiyama.yui.cr@mail.hosp.go.jp |
Sponsor | |
Institute | Department of Clinical Research, Tokushima National Hospital National Hospital Organization |
Institute | |
Department |
Funding Source | |
Organization | Department of Clinical Research, Tokushima National Hospital National Hospital Organization |
Organization | |
Division | |
Category of Funding Organization | Other |
Nationality of Funding Organization |
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Co-sponsor | |
Name of secondary funder(s) |
IRB Contact (For public release) | |
Organization | Tokushima National Hospital National Hospital Organization |
Address | 1354 Shikiji, Kamojima, Yoshinogawa, Tokushima |
Tel | 0883-24-2161 |
mukaiyama.yui.cr@mail.hosp.go.jp |
Secondary IDs | |
Secondary IDs | NO |
Study ID_1 | |
Org. issuing International ID_1 | |
Study ID_2 | |
Org. issuing International ID_2 | |
IND to MHLW |
Institutions | |
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Date of disclosure of the study information |
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Related information | |
URL releasing protocol | |
Publication of results | Unpublished |
Result | |
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Baseline Characteristics | |
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IPD sharing Plan description |
Progress | |||||||
Recruitment status | Open public recruiting | ||||||
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Other | |
Other related information | Outpatients and Inpatients at Tokushima National Hospital |
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Last modified on |
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Link to view the page | |
URL(English) | https://upload.umin.ac.jp/cgi-open-bin/ctr_e/ctr_view.cgi?recptno=R000047888 |
Research Plan | |
Registered date | File name |
Research case data specifications | |
Registered date | File name |
Research case data | |
Registered date | File name |