UMIN-CTR Clinical Trial

Public title

Effect of repetitions of strength training on muscle hypertrophy in untrained healthy young adults

Acronym

Effect of repetitions of strength training on muscle hypertrophy in untrained healthy young adults

Scientific Title

Dose-response of repetitions of resistance training on muscle hypertrophy in untrained healthy young adults

Scientific Title:Acronym

Dose-response of repetitions of resistance training on muscle hypertrophy in untrained healthy young adults

Region

Japan

Condition

Healthy adults

Classification by specialty

Rehabilitation medicine

Adult

Classification by malignancy

Others

Genomic information

NO

Narrative objectives1

he aim of this study is to compare the effect of 3, 5, 7, and 10 repetitions per 1 set on the change of muscle hypertrophy due to 12 weeks resistance training in untrained healthy young adults, and to clarify that there is a dose-response relationship between repetitions and the changes in muscle hypertrophy .

Basic objectives2

Efficacy

Basic objectives -Others

Trial characteristics_1

Trial characteristics_2

Developmental phase

Primary outcomes

Muscle mass 12 weeks after the start of the intervention

Key secondary outcomes

Muscle strength 12 weeks after the start of the intervention
Muscle thickness 12 weeks after the start of the intervention

Study type

Interventional

Basic design

Parallel

Randomization

Randomized

Randomization unit

Individual

Blinding

Open -no one is blinded

Control

No treatment

Stratification

Dynamic allocation

Institution consideration

Blocking

Concealment

No. of arms

5

Purpose of intervention

Educational,Counseling,Training

Type of intervention

Other

Interventions/Control_1

Subjects perform leg press and chest press, with training performed twice a week for 12 weeks. This group is performed 3 set x 10 repetitions at training load of 10 repetition maximum(RM).

Interventions/Control_2

Subjects perform leg press and chest press, with training performed twice a week for 12 weeks. This group is performed 3 set x 7 repetitions at training load of 10 RM.

Interventions/Control_3

Subjects perform leg press and chest press, with training performed twice a week for 12 weeks. This group is performed 3 set x 5 repetitions at training load of 10 RM.

Interventions/Control_4

Subjects perform leg press and chest press, with training performed twice a week for 12 weeks. This group is performed 3 set x 3 repetitions at training load of 10 RM.

Interventions/Control_5

Control

Interventions/Control_6

Interventions/Control_7

Interventions/Control_8

Interventions/Control_9

Interventions/Control_10

Age-lower limit

18

years-old

<=

Age-upper limit

35

years-old

>=

Gender

Male and Female

Key inclusion criteria

Subjects who have not been regularly resistance training for the past year

Key exclusion criteria

Subjects with orthopedic diseases or their history that may interfere with resistance training
Subjects with nervous system diseases or their history that may interfere with resistance training
Subjects with internal medical diseases or their history that may interfere with resistance training
Subjects with other subjective symptoms that may interfere with resistance training
Subjects using a pacemaker
Subjects judged by the principal investigator to be inappropriate as subjects

Target sample size

90

Name of lead principal investigator

1st name	Hotaka
Middle name
Last name	Sugimoto

Organization

Shinshu university

Division name

Department of Physical Therapy

Zip code

390-8621

Address

3-1-1 Asahi, Matsumoto, Nagano

TEL

+81-263-37-2413

Email

hsugimoto@shinshu-u.ac.jp

Name of contact person

1st name	Hotaka
Middle name
Last name	Sugimoto

Organization

Shinshu university

Division name

Department of Physical Therapy

Zip code

390-8621

Address

3-1-1 Asahi, Matsumoto, Nagano

TEL

+81-263-37-2413

Homepage URL

Email

hsugimoto@shinshu-u.ac.jp

Institute

Shinshu university

Institute

Department

Personal name

Organization

None

Organization

Division

Category of Funding Organization

Self funding

Nationality of Funding Organization

Co-sponsor

Name of secondary funder(s)

Organization

Shinshu University School of Medicine Ethics Committee Secretariat

Address

3-1-1 Asahi, Matsumoto, Nagano

Tel

+81-263-37-2572

Email

mdrinri@shinshu-u.ac.jp

Secondary IDs

NO

Study ID_1

Org. issuing International ID_1

Study ID_2

Org. issuing International ID_2

IND to MHLW

Institutions

Date of disclosure of the study information

2020

Year

10

Month

15

Day

URL releasing protocol

Publication of results

Unpublished

URL related to results and publications

Number of participants that the trial has enrolled

Results

Results date posted

Results Delayed

Results Delay Reason

Date of the first journal publication of results

Baseline Characteristics

Participant flow

Adverse events

Outcome measures

Plan to share IPD

IPD sharing Plan description

Recruitment status

Open public recruiting

Date of protocol fixation

2020

Year

08

Month

27

Day

Date of IRB

2020

Year

10

Month

12

Day

Anticipated trial start date

2020

Year

10

Month

15

Day

Last follow-up date

2025

Year

09

Month

30

Day

Date of closure to data entry

Date trial data considered complete

Date analysis concluded

Other related information

Registered date

2020

Year

10

Month

14

Day

Last modified on

2022

Year

04

Month

15

Day

Link to view the page

Value
https://center6.umin.ac.jp/cgi-open-bin/ctr_e/ctr_view.cgi?recptno=R000048056