Unique ID issued by UMIN | UMIN000043106 |
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Receipt number | R000048712 |
Scientific Title | Study of chewing and tear production in healthy young subjects |
Date of disclosure of the study information | 2021/01/23 |
Last modified on | 2021/02/15 13:00:09 |
Relationship between chewing and tear production in healthy young subjects
Relationship between chewing and tear production in healthy subjects
Study of chewing and tear production in healthy young subjects
Study of chewing and tear production in healthy subjects
Japan |
healthy adult
Adult |
Others
NO
To investigate the effects of chewing for tear production in healthy young subjects.
Efficacy
Value of tear production before and after chewing gum
Interventional
Cross-over
Randomized
Individual
Open -no one is blinded
No treatment
2
Treatment
Food |
Gum chewing of two pieces during Schirmer I test with topical anesthesia (once, max 5 minutes).
No gum chewing during Schirmer I test with topical anesthesia (once, max 5 minutes)
20 | years-old | <= |
30 | years-old | > |
Male and Female
(1) Twenty four eyes of 12 healthy subjects between 20 and 29 years old.
(1) Subjects who do not like the mint taste.
(2) Subjects who inability to chew gum.
(3) Subjects with sufficiently severe dry eye such that refraining from blinking for 5 seconds was impossible.
(4) Subjects had side effects (hyperemia and corneal erosion) caused by oxybuprocaine hydrochloride.
12
1st name | Ken |
Middle name | |
Last name | Asakawa |
School of Allied Health Sciences, Kitasato University
Department of Orthoptics and Visual Science
252-0373
1-15-1 Kitasato, Sagamihara, Minami-ku, Kanagawa
042-778-9667
asaken@kitasato-u.ac.jp
1st name | Ken |
Middle name | |
Last name | Asakawa |
School of Allied Health Sciences, Kitasato University
Department of Orthoptics and Visual Science
252-0373
1-15-1 Kitasato, Sagamihara, Minami-ku, Kanagawa
042-778-9667
asaken@kitasato-u.ac.jp
Kitasato University
Kitasato University
Other
School of Allied Health Sciences, Kitasato University
1-15-1 Kitasato, Sagamihara, Minami-ku, Kanagawa
042-778-9602
a-soumu@kitasato-u.ac.jp
NO
2021 | Year | 01 | Month | 23 | Day |
Published
16
Completed
2020 | Year | 10 | Month | 27 | Day |
2021 | Year | 01 | Month | 22 | Day |
2021 | Year | 01 | Month | 23 | Day |
2021 | Year | 03 | Month | 12 | Day |
2021 | Year | 01 | Month | 23 | Day |
2021 | Year | 02 | Month | 15 | Day |
Value
https://center6.umin.ac.jp/cgi-open-bin/ctr_e/ctr_view.cgi?recptno=R000048712
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