Unique ID issued by UMIN | UMIN000042811 |
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Receipt number | R000048876 |
Scientific Title | Network meta-analysis of adjuvant chemotherapy for NSCLC |
Date of disclosure of the study information | 2020/12/22 |
Last modified on | 2020/12/22 11:44:28 |
Network meta-analysis of adjuvant chemotherapy for NSCLC
Adjuvant Chemotherapy for NSCLC
Network meta-analysis of adjuvant chemotherapy for NSCLC
Adjuvant Chemotherapy for NSCLC
Japan |
Early-stage non-small cell lung cancer
Pneumology |
Malignancy
NO
The primary aim of this study is to assess if Cis-Pemt prolong recurrence-free survival compared to observation using indirect comparison. Besides, comparison of safety profile between Cis-Vnr and Cis-Pemt is secondarily evaluated.
Safety,Efficacy
The primary endpoint is recurrence-free survival assessed by hazard ratio.
Others,meta-analysis etc
Not applicable |
Not applicable |
Male and Female
Patient should have early stage (stage I-IIIa) NSCLC. Sub-pathological type of NSCLC is not questioned. Patients in at least one arm need to be treated with Cis-Vnr or Cis-Pemt. Dose and number of planned cycles of the chemotherapy are not questioned.
Neoadjuvant chemotherapy or pre-operative chemotherapy is not our concern.
1st name | Nobuyuki |
Middle name | |
Last name | Horita |
Yokohama City University
Department of Pulmonology
235-0016
3-9, Fukuura, Kanazawa, Yokohama, Japan
+81457872800
horitano@yokohama-cu.ac.jp
1st name | Nobuyuki |
Middle name | |
Last name | Horita |
Yokohama City University
Department of Pulmonology
235-0016
3-9, Fukuura, Kanazawa, Yokohama, Japan
+81457872800
horitano@yokohama-cu.ac.jp
Self sponsored
None
Self funding
Yokohama City University
3-9, Fikuura, Kanazawa, Yokohama, Japan
0457872800
nobuyuki_horita@yahoo.co.jp
NO
2020 | Year | 12 | Month | 22 | Day |
Unpublished
Preinitiation
2020 | Year | 12 | Month | 22 | Day |
2020 | Year | 12 | Month | 22 | Day |
2021 | Year | 12 | Month | 31 | Day |
The following search formula will be used for PubMed: (pemetrexed or vinorelbine) (non-small cell lung cancer or NSCLC) (adjuvant or neoadjuvant or post-surgery or post-operation) (randomized or randomised or RCT or randomly). Hand search for the NCCN, ASCO, and ESMO guidelines are planned.
The frequentist weighted least-squares approach random-model network meta-analysis was performed using R software (Command: netmeta, Package: netmeta) for the primary endpoint.
2020 | Year | 12 | Month | 22 | Day |
2020 | Year | 12 | Month | 22 | Day |
Value
https://center6.umin.ac.jp/cgi-open-bin/ctr_e/ctr_view.cgi?recptno=R000048876
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