Unique ID issued by UMIN | UMIN000042873 |
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Receipt number | R000048935 |
Scientific Title | Open-label crossover trial for the efficacy and safety of switching to HIF-PH inhibitor in anemic patients with maintenance hemodialysis treated by ESA. |
Date of disclosure of the study information | 2021/01/05 |
Last modified on | 2023/01/03 17:04:02 |
Open-label crossover trial for the efficacy and safety of switching to HIF-PH inhibitor in anemic patients with maintenance hemodialysis treated by ESA.
HIF-PH anemia study
Open-label crossover trial for the efficacy and safety of switching to HIF-PH inhibitor in anemic patients with maintenance hemodialysis treated by ESA.
HIF-PH anemia study
Japan |
hemodialysis patient
Nephrology |
Others
NO
To assess the efficacy and safety of switching to a HIF-PH inhibitor in patients using Darbepoetin.
Safety,Efficacy
Not applicable
Hb
Fe,ferritin,TSAT
Interventional
Cross-over
Non-randomized
Open -no one is blinded
Active
2
Treatment
Medicine |
After treatment with Roxadustat for 12 weeks, change to the therapy of Daprodustat for 12 weeks.
After treatment with Daprodustat for 12 weeks, change to the therapy of Roxadustat for 12 weeks.
Not applicable |
Not applicable |
Male and Female
1.Patients treated with Darbepoetin Alfa for more than 3 months before the trial.
2.Patients with stable hemoglobin level before the trial.
3.Maintenance hemodialysis and hemodiafiltration patients, three times a week.
1.Patients who have difficulty in taking oral medicine.
2.Patients on concomitant peritoneal dialysis.
3.Patients judged by the investigator to be unsuitable as subjects.
40
1st name | misaki |
Middle name | |
Last name | moriishi |
Nakajima tsuchiya clinic
dialysis treatment center
730-0811
6-1,Nakajima-cho,Naka-ku,Hiroshima-shi,Hiroshima
082-542-7271
usagi@tsuchiya-hp.jp
1st name | misaki |
Middle name | |
Last name | moriishi |
Nakajima tsuchiya clinic
dialysis treatment center
730-0811
6-1,Nakajima-cho,Naka-ku,Hiroshima-shi,Hiroshima
082-542-7271
usagi@tsuchiya-hp.jp
Nakajima tsuchiya clinic
none
Other
Tsuchiya general hospital ehic screening committee
3-30,Nakajima-cho,Naka-ku,Hiroshima-shi,Hiroshima
082-542-9191
jyamamoto@tsuchiya-hp.jp
NO
2021 | Year | 01 | Month | 05 | Day |
Unpublished
Completed
2020 | Year | 11 | Month | 09 | Day |
2020 | Year | 11 | Month | 16 | Day |
2020 | Year | 11 | Month | 17 | Day |
2021 | Year | 12 | Month | 31 | Day |
2020 | Year | 12 | Month | 29 | Day |
2023 | Year | 01 | Month | 03 | Day |
Value
https://center6.umin.ac.jp/cgi-open-bin/ctr_e/ctr_view.cgi?recptno=R000048935
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