Unique ID issued by UMIN | UMIN000043365 |
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Receipt number | R000049516 |
Scientific Title | The Effect of Vitamin C Supplementation on Plasma Vitamin C Levels after Scaling and Rootplaning in Periodontitis-Smokers |
Date of disclosure of the study information | 2021/12/20 |
Last modified on | 2021/02/18 14:22:05 |
The Effect of Vitamin C Supplementation on Plasma Vitamin C levels after Scaling and Rootplaning in Periodontitis-Smokers
Vitamin C Supplementation on Plasma Vitamin C levels after SRP in Periodontitis-Smokers
The Effect of Vitamin C Supplementation on Plasma Vitamin C Levels after Scaling and Rootplaning in Periodontitis-Smokers
The Effect of Vitamin C Supplementation on Plasma Vitamin C Levels after Scaling and Rootplaning in Periodontitis-Smokers : Vitamin C Supplementation on Plasma Vitamin C levels after SRP in Periodontitis-Smokers
Asia(except Japan) |
Healthy-adult smokers, with chronic periodontitis
Dental medicine |
Others
NO
To analyse the effect of vitamin C supplementation and the impact of one visit full-mouth debridement (scaling and rootplaning)on plasma vitamin C levels in smokers with chronic periodontitis
Efficacy
Exploratory
Explanatory
Not applicable
Plasma Vitamin C Levels
Periodontal Probing depth
Interventional
Parallel
Randomized
Individual
Double blind -all involved are blinded
Placebo
NO
NO
Institution is not considered as adjustment factor.
NO
Central registration
2
Treatment
Other |
The test group received scaling and rootplaning and 320 mg vitamin C (Ester C) once a day, 30 days before and after scaling and rootplaning (in total 60 days of supplementation)
The control group received scaling and rootplaning and placebo once a day, 30 days before and after scaling and rootplaning (in total 60 days of supplementation)
30 | years-old | <= |
65 | years-old | > |
Male and Female
1. Systemically healthy adults;
2. > 30 years old and < 65 years old;
3. Being a smoker (10 cigarettes/day for more than 5 years);
4. Having chronic periodontitis (having pocket depth more than 5 mm at least at 2 teeth in maxilla and/or mandible)
1. had a systemic disease;
2. had a course of non steroidal anti inflammatory drugs or antimicrobial drugs within a 3-month period before the study began;
3. were pregnant or lactating;
4. used mouth-washes or vitamin supplements within the previous 3 months;
5. underwent periodontal treatment within a 3-month period before study began;
6. were using any orthodontic or prosthodontic appliances.
30
1st name | Amaliya |
Middle name | |
Last name | Amaliya |
Dental Faculty - Universitas Padjadjaran Indonesia
Periodontology
40132
Jalan Sekeloa Selatan no. 1 Bandung - West Java
0062222504985
amaliya@fkg.unpad.ac.id
1st name | Amaliya |
Middle name | |
Last name | Amaliya |
Dental Faculty - Universitas Padjadjaran - Indonesia
Periodontology
40132
Jalan Sekeloa Selatan no. 1 Bandung 40132 - West Java
0062222504985
amaliya@fkg.unpad.ac.id
Dental Faculty - Universitas Padjadjaran Indonesia
Periodontology Departement
Self-funding
Self funding
Indonesia
Research Ethics Commitee of Universitas Padjadjaran
Jalan Prof. Eijkman No. 38, 4th floor, West Wing, Bandung
0062222038697
etik.unpad@gmail.com
NO
Dental and Oral Hospital Universitas Padjadjaran Indonesia
2021 | Year | 12 | Month | 20 | Day |
Unpublished
30
In the test group, plasma vitamin C levels significantly increased after supplementation and scaling and root planing did not have impact in decreasing these levels, whereas in the control group, plasma vitamin C levels did not elevate and after scaling and rootplaning it declined significantly.
2021 | Year | 02 | Month | 18 | Day |
None were reported
Plasma vitamin C levels
Probing pocket depth
No longer recruiting
2019 | Year | 02 | Month | 09 | Day |
2019 | Year | 03 | Month | 13 | Day |
2019 | Year | 12 | Month | 01 | Day |
2020 | Year | 03 | Month | 30 | Day |
2020 | Year | 04 | Month | 10 | Day |
2020 | Year | 04 | Month | 20 | Day |
2020 | Year | 04 | Month | 30 | Day |
2021 | Year | 02 | Month | 18 | Day |
2021 | Year | 02 | Month | 18 | Day |
Value
https://center6.umin.ac.jp/cgi-open-bin/ctr_e/ctr_view.cgi?recptno=R000049516
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