Unique ID issued by UMIN | UMIN000043366 |
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Receipt number | R000049518 |
Scientific Title | Portal hemodynamic effects of atezolizumab and bevacizumab in patients with advanced hepatocellular carcinoma: a prospective cohort study |
Date of disclosure of the study information | 2021/02/18 |
Last modified on | 2021/02/18 15:06:53 |
Portal hemodynamic effects of atezolizumab and bevacizumab in patients with advanced hepatocellular carcinoma: a prospective cohort study
Portal hemodynamic effects of atezolizumab and bevacizumab
Portal hemodynamic effects of atezolizumab and bevacizumab in patients with advanced hepatocellular carcinoma: a prospective cohort study
Portal hemodynamic effects ofatezolizumab and bevacizumab
Japan |
patients with advanced hepatocellular carcinoma
Hepato-biliary-pancreatic medicine |
Malignancy
NO
Evaluation of the portal hemodynamic effect of atezolizumab and bevacizumab in patients with advanced HCC
Safety,Efficacy
Changes in portal venous area
Interventional
Single arm
Non-randomized
Open -no one is blinded
Uncontrolled
1
Treatment
Medicine |
1200 mg of atezolizumab plus 15 mg per kilogram of body weight of bevacizumab intravenously every 3 weeks
20 | years-old | <= |
Not applicable |
Male
1) Advanced-stage HCC is confirmed by clinical analysis.
2) BCLC stage B2 or B3
1)Tumor invasion in intrahepatic large vessels (Vp4)
2)hepatic encephalopathy, refractory ascites
3)hypertension (160/100 or higher.)
4)Severe renal function(eGFR<50ml/min)
50
1st name | Hidaka |
Middle name | |
Last name | Hisashi |
Kitasato University School of Medicine
Department of Gastroenterology, Internal Medicine
252-0373
1-15-1 Kitasato, Minami-ku, Sagamihara, Kanagawa 252-0380, Japan
+81-42-778-7750
hisashi7@kitasato-u.ac.jp
1st name | Haruki |
Middle name | |
Last name | Uojima |
Kitasato University School of Medicine
Department of Gastroenterology, Internal Medicine
252-0374
1-15-1 Kitasato, Minami-ku, Sagamihara, Kanagawa 252-0380, Japan
0427788111
kiruha@kitasato-u.ac.jp
Kitasato University School of Medicine
Kitasato University School of Medicine
Self funding
Kitasato University School of Medicine Institutional Review Board
1-15-1 Kitasato, Minami-ku, Sagamihara, Kanagawa 252-0380, Japan
0427788111
kiruha@kitasato-u.ac.jp
NO
2021 | Year | 02 | Month | 18 | Day |
Unpublished
Open public recruiting
2021 | Year | 02 | Month | 03 | Day |
2021 | Year | 02 | Month | 18 | Day |
2021 | Year | 02 | Month | 18 | Day |
2026 | Year | 02 | Month | 18 | Day |
2021 | Year | 02 | Month | 18 | Day |
2021 | Year | 02 | Month | 18 | Day |
Value
https://center6.umin.ac.jp/cgi-open-bin/ctr_e/ctr_view.cgi?recptno=R000049518
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