Unique ID issued by UMIN | UMIN000043445 |
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Receipt number | R000049611 |
Scientific Title | Effect of lactulose ingestion on ammonia gas emitted from human skin. |
Date of disclosure of the study information | 2021/02/26 |
Last modified on | 2021/08/30 10:15:46 |
Effect of lactulose ingestion on ammonia gas emitted from human skin.
Effect of lactulose ingestion on ammonia gas emitted from human skin.
Effect of lactulose ingestion on ammonia gas emitted from human skin.
Effect of lactulose ingestion on ammonia gas emitted from human skin.
Japan |
Not applicable
Not applicable | Adult |
Others
NO
To evaluate the skin ammonia gas emission inhibitory effect of a single ingestion of 4 g of lactulose under protein loading conditions.
Efficacy
Confirmatory
Others
Not applicable
Emission flux of Ammonia gas from human skin (AUC)
Emission flux of Ammonia gas from human skin (Peak value), Stool forms
Interventional
Cross-over
Randomized
Individual
Open -no one is blinded
Placebo
YES
NO
No need to know
2
Treatment
Food |
Single intake of 4g lactulose
Single intake of placebo
20 | years-old | <= |
65 | years-old | > |
Male and Female
Healthy people
1) Subjects with severe hepatic, renal, heart, gastrointestinal, cerebrovascular, endocrine, metabolic or infection diseases.
2) Subjects with the history of gastrointestinal resection.
3) Subjects with gastrointestinal dysfunction such as irritable bowel syndrome or inflammatory bowel disease.
4) Subjects who use medicines or supplements that may influence feces frequency; e.g. antibiotics, probiotics, laxatives, antidiarrheals, fibers.
5) Subjects with milk allergy, metal allergy, or lactose intolerance.
6) Subjects who participate another study.
7) Subjects who are judged inappropriate for the study by the investigator or the physician.
20
1st name | Yoshika |
Middle name | |
Last name | Sekine |
Tokai University
Graduate School of Science
259-1207
4-1-1 Kitakaname, Hiratsuka-shi, Kanagawa
0463-58-1211
sekine@keyaki.cc.u-tokai.ac.jp
1st name | Yoshika |
Middle name | |
Last name | Sekine |
Tokai University
Graduate School of Science
259-1207
4-1-1 Kitakaname, Hiratsuka-shi, Kanagawa
0463-58-1211
sekine@keyaki.cc.u-tokai.ac.jp
Tokai University
Morinaga Milk Industry Co., LTD.
Profit organization
TOKAI DAIGAKU " hito wo taisho to suru kenkyu"ni kansuru rinriiinnkai
4-1-1 Kitakaname, Hiratsuka-shi, Kanagawa
0463-58-1211
sekine@keyaki.cc.u-tokai.ac.jp
NO
2021 | Year | 02 | Month | 26 | Day |
Unpublished
Completed
2021 | Year | 02 | Month | 17 | Day |
2021 | Year | 02 | Month | 25 | Day |
2021 | Year | 02 | Month | 26 | Day |
2021 | Year | 03 | Month | 24 | Day |
2021 | Year | 02 | Month | 26 | Day |
2021 | Year | 08 | Month | 30 | Day |
Value
https://center6.umin.ac.jp/cgi-open-bin/ctr_e/ctr_view.cgi?recptno=R000049611
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