Unique ID issued by UMIN | UMIN000043770 |
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Receipt number | R000049964 |
Scientific Title | The effect of povidone iodine (PVP-I) on thyroid function. Preliminary Study: Iodine intake from iodine mouthwash by gargling. |
Date of disclosure of the study information | 2021/03/29 |
Last modified on | 2024/04/17 20:03:55 |
The effect of oral disinfectant containing iodine on thyroid function. Preliminary Study: Iodine intake from mouthwash and antiseptic solution.
The effect of iodine intake from mouthwash and antiseptic spray on thyroid function.
The effect of povidone iodine (PVP-I) on thyroid function. Preliminary Study: Iodine intake from iodine mouthwash by gargling.
Iodine intake from PVP-I gargling or spraying.
Japan |
thyroid dysfunction
Endocrinology and Metabolism | Adult |
Others
NO
To elucidate the effect of oral disinfectant containing povidone iodine on thyroid function. As a preliminary study the amount of iodine absorbed by gargling or spraying with mouthwash containing povidone iodine is determined.
Bio-availability
1. The absolute amount and ratio of mouthwash absorbed by standardized gargling.
2. The absolute amount and ratio of iodine absorbed by gargling.
Interventional
Single arm
Non-randomized
Open -no one is blinded
Uncontrolled
1
Prevention
Medicine |
Gargle by standarized method with mouthwash containing PVP-I or distilled water.
Measure the amount and ratio of volume and iodine content in the fluid before and after gargling.
20 | years-old | <= |
Not applicable |
Male and Female
Heathy adults
Denture, oral cavity diseases, dysphagia
30
1st name | YOZEN |
Middle name | |
Last name | FUSE |
Foundation for Growth Science
Research committee on iodine related health problems
1130033
5-1-16 Hongo, Bunkyou-ku, Tokyo
0358055370
fuseyz@hotmai.com
1st name | YOZEN |
Middle name | |
Last name | FUSE |
Foundation for Growth Science
Research committee on iodine related health problems
1130033
5-1-16 Hongo, Bunkyou-ku, Tokyo
0358055370
fuseyz@hotmai.com
Research committee on iodine related health problems, Foundation for Growth Science
None
Other
Japanese Red Cross Hokkaido College of Nursing
664-1 Asahicho, Kitami City, Hokkaido
0157-66-3311
yito@rchokkaido-cn.ac.jp
NO
2021 | Year | 03 | Month | 29 | Day |
DOI : 10.1007/s12011-021-02978-7
Published
DOI : 10.1007/s12011-021-02978-7
22
Around 5 mg of iodine could theoretically enter the body with one gargle which exceeds the tolerable upper intake level of iodine for adults.
2024 | Year | 04 | Month | 17 | Day |
Healthy aduts without thyroid disease
none
none
Iodine content absorbed into the body
Completed
2020 | Year | 12 | Month | 01 | Day |
2021 | Year | 02 | Month | 25 | Day |
2021 | Year | 02 | Month | 26 | Day |
2022 | Year | 03 | Month | 31 | Day |
2021 | Year | 03 | Month | 28 | Day |
2024 | Year | 04 | Month | 17 | Day |
Value
https://center6.umin.ac.jp/cgi-open-bin/ctr_e/ctr_view.cgi?recptno=R000049964
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