Unique ID issued by UMIN | UMIN000044077 |
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Receipt number | R000050325 |
Scientific Title | Combination of Tryptase and IL-33 in Bronchoalveolar Lavage Fluid May Predict the Types of Eosinophilic Pneumonia and Disease Recurrence |
Date of disclosure of the study information | 2021/04/29 |
Last modified on | 2021/04/29 22:31:31 |
Combination of Tryptase and IL-33 in Bronchoalveolar Lavage Fluid May Predict the Types of Eosinophilic Pneumonia and Disease Recurrence
Tryptase and IL-33 in BALF of EP patients
Combination of Tryptase and IL-33 in Bronchoalveolar Lavage Fluid May Predict the Types of Eosinophilic Pneumonia and Disease Recurrence
Tryptase and IL-33 in BALF of EP patients
Japan |
Patients diagnosed with eosinophilic pneumonia
Pneumology |
Others
NO
We aimed to evaluate the differences in tryptase and Interleukin-33 (IL-33) levels in bronchoalveolar lavage fluid (BALF) among several types of EP. We also evaluated the differences in these biomarkers between the recurrent and non-recurrent cases.
Bio-availability
tryptase and IL-33 in BALF
Observational
20 | years-old | <= |
Not applicable |
Male and Female
Patients who was diagnosed with eosinophilic pneumonia
history of malignancy, idiopathic eosinophilia
35
1st name | Tomohiro |
Middle name | |
Last name | Akaba |
Tokyo Women's Medical University
Department of respiratory medicine
162-0054
8-1 Kawada-cho, Shinjuku-ku, Tokyo
81-3-3353-8111
akaba.tomohiro@twmu.ac.jp
1st name | Tomohiro |
Middle name | |
Last name | Akaba |
Tokyo Women's Medical University
Department of respiratory medicine
162-0054
8-1 Kawada-cho, Shinjuku-ku, Tokyo
81-3-3353-8111
akaba.tomohiro@twmu.ac.jp
Tokyo Women's Medical University
self funding
Self funding
Tokyo Women's Medical University IRB
8-1 Kawada-cho, Shinjuku-ku, Tokyo
81-3-3353-8111
rinri.bm@twmu.ac.jp
NO
2021 | Year | 04 | Month | 29 | Day |
https://upload.umin.ac.jp/cgi-bin/ctr/ctr_up_rec_f5.cgi
Partially published
https://upload.umin.ac.jp/cgi-bin/ctr/ctr_up_rec_f5.cgi
35
We enrolled 15 patients with chronic EP (CEP), 5 with acute EP (AEP), 10 with drug-induced EP, and 6 with angiitis-related EP.
2021 | Year | 04 | Month | 29 | Day |
Patients diagnosed with eosinophilic pneumonia were enrolled.
Patients diagnosed with eosinophilic pneumonia were enrolled.
N/A
We enrolled 15 patients with chronic EP (CEP), 5 with acute EP (AEP), 10 with drug-induced EP, and 6 with angiitis-related EP.
Completed
2006 | Year | 01 | Month | 01 | Day |
2006 | Year | 01 | Month | 01 | Day |
2006 | Year | 01 | Month | 01 | Day |
2015 | Year | 12 | Month | 31 | Day |
We prospectively collected the clinical data of patients with EP diagnosed between 2006 and 2015 in our institution. Bronchoscopy was performed before steroid treatment, and BALF was collected. The clinical characteristics of EP patients and tryptase and IL-33 levels in BALF were evaluated.
2021 | Year | 04 | Month | 29 | Day |
2021 | Year | 04 | Month | 29 | Day |
Value
https://center6.umin.ac.jp/cgi-open-bin/ctr_e/ctr_view.cgi?recptno=R000050325
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