Unique ID issued by UMIN | UMIN000044374 |
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Receipt number | R000050688 |
Scientific Title | A prospective study examining the effect of brolcizumab on neovascular age-related macular degeneration in Japanese with treat and extend |
Date of disclosure of the study information | 2021/05/31 |
Last modified on | 2023/11/20 13:27:44 |
A study examining the effect of the brolcizumab
on neovascular age-related macular degeneration in Japanese with treat and extend
brolcizumab on nAMD in Japanese with treat and extend
A prospective study examining the effect of brolcizumab on neovascular age-related macular degeneration in Japanese with treat and extend
A prospective stud ; brolcizumab on nAMD in Japanese with treat and extend
Japan |
neovascular age-related macular degeneration
Ophthalmology |
Others
NO
To confirm the efficacy and safety of brolcizumab on neovascylar age-related macular degeneration in Japanese.
Safety,Efficacy
Percentage of patients with visual acuity and dosing interval extended to 12 weeks after 12 or 24 months
Observational
50 | years-old | <= |
89 | years-old | > |
Male and Female
choroidal neovascularization due to exudative age-related macular degeneration is confirmed by FA/IA within 3000 micro meter centered on the fovea centralis.
Visual acuity is reduced due to exudative changes in the macula.
Within 6 months of onset
There is consent for this research
Untreated
Eye surgery within 3 months
There are other disorders that cause vision loss
History of vitreous surgery
History of grid-like photocoagulation
History of cerebrocardiovascular events within 6 months
Adults who are judged to lack informed consent
Doctor judges that it is not suitable for this study
50
1st name | Hidenori |
Middle name | |
Last name | Takahashi |
Jichi Medical University
Ophthalmology
3290498
Tochigi, Shimotsuke city Yakushiji 3311-1
0285587382
takahah-tky@umin.ac.jp
1st name | Satoru |
Middle name | |
Last name | Inoda |
Jichi Medical University
Ophthalmology
3290498
Tochigi, Shimotsuke city Yakushiji 3311-1
0285587382
r1208is@jichi.ac.jp
Jichi Medical University
Jichi Medical University
Other
Haga Japanese Red Cross Hospital
Sano City Hospital, Sano-shi
Jichi Medical University Clinical Research Ethics Committee
Tochi Shimotsuke Yakashiji 3311-1
0285-58-8933
jrinri@jichi.ac.jp
NO
2021 | Year | 05 | Month | 31 | Day |
Unpublished
50
Completed
2020 | Year | 10 | Month | 10 | Day |
2020 | Year | 11 | Month | 06 | Day |
2020 | Year | 11 | Month | 06 | Day |
2023 | Year | 09 | Month | 30 | Day |
2023 | Year | 10 | Month | 20 | Day |
2023 | Year | 10 | Month | 20 | Day |
2023 | Year | 10 | Month | 20 | Day |
Gender, age, pre-treatment and up to 24 months after treatment, visual acuity, fundus photograph, optical coherence tomography, maximum corrected visual acuity, retinal film thickness, and number of consultations. In addition, as a type of wet age-related macular degeneration, typical AMD, polypoid choroidal angiopathy, diagnostic classification of retinal hemangiomatous growth, and frequency of vitreous injection administration
2021 | Year | 05 | Month | 30 | Day |
2023 | Year | 11 | Month | 20 | Day |
Value
https://center6.umin.ac.jp/cgi-open-bin/ctr_e/ctr_view.cgi?recptno=R000050688
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