Unique ID issued by UMIN | UMIN000054227 |
---|---|
Receipt number | R000061918 |
Scientific Title | Study of platelet thrombosis by Hyperglycemia of healthy individuals after intake. |
Date of disclosure of the study information | 2024/04/24 |
Last modified on | 2024/04/22 21:31:04 |
Study of the potential for elevated postprandial blood glucose to cause thrombosis in healthy individuals.
Thrombosis risk after eating in healthy individuals
Study of platelet thrombosis by Hyperglycemia of healthy individuals after intake.
Thrombosis risk after eating in healthy individuals
Japan |
healthy indivisuals
Adult |
Others
NO
In this study, we will determine the effects of elevated blood glucose following sugar ingestion on platelet thrombus formation in healthy subjects.
Others
We will clarify the effects of conditions that inhibit glucose metabolism (especially ATP synthesis) during hyperglycemia on thrombus formation.
The growth of platelet thrombosis on collagen fibrils before and after glucose intake is observed by using a fluorescence microscope under conditions of blood flow shear rate (1500 s-1) equivalent to human arterial blood flow.
The platelet thrombus is to be evaluated for both the area and fluorescence density of each single thrombus by software Image J.
Interventional
Single arm
Non-randomized
Open -no one is blinded
Self control
1
Prevention
Food |
Glucose solution for healthy subjects
18 | years-old | <= |
60 | years-old | >= |
Male and Female
healthy individuals
Persons taking antiplatelet drugs.
Persons with high blood glucose levels during fasting.
15
1st name | Noriko |
Middle name | |
Last name | Tamura |
Niigata University of Health and Welfare
Department of Health and Nutrition, Faculty of Health Sciences
9503198
1398 Shimami-cho, Kita-ku, Niigata, 950-3198 Japan
0252574478
noriko-tamura@nuhw.ac.jp
1st name | Noriko |
Middle name | |
Last name | Tamura |
Niigata University of Health and Welfare
Department of Health and Nutrition, Faculty of Health Sciences
9503198
1398 Shimami-cho, Kita-ku, Niigata, 950-3198 Japan
0252574478
noriko-tamura@nuhw.ac.jp
other
other
Other
Niigata University of Health and Welfare Ethics Review Committee
1398 Shimami-cho, Kita-ku, Niigata, 950-3198 Japan
0252574455
rinri@nuhw.ac.jp
NO
2024 | Year | 04 | Month | 24 | Day |
Unpublished
Preinitiation
2024 | Year | 05 | Month | 18 | Day |
2024 | Year | 06 | Month | 01 | Day |
2026 | Year | 03 | Month | 31 | Day |
2024 | Year | 04 | Month | 22 | Day |
2024 | Year | 04 | Month | 22 | Day |
Value
https://center6.umin.ac.jp/cgi-open-bin/ctr_e/ctr_view.cgi?recptno=R000061918
Research Plan | |
---|---|
Registered date | File name |
Research case data specifications | |
---|---|
Registered date | File name |
Research case data | |
---|---|
Registered date | File name |