Unique ID issued by UMIN | UMIN000034121 |
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Receipt number | R000033251 |
Scientific Title | Development of the vascular rehabilitation method based on the vascular endthelial function mesurement |
Date of disclosure of the study information | 2018/09/14 |
Last modified on | 2024/03/18 09:33:25 |
Development of the vascular rehabilitation method based on the vascular endthelial function mesurement
Development of the vascular rehabilitation method
Development of the vascular rehabilitation method based on the vascular endthelial function mesurement
Development of the vascular rehabilitation method
Japan |
patients of life style related diseases or pre-life style related diseases
Medicine in general | Rehabilitation medicine |
Others
NO
This study aim to investigate the most effective exercise method for the vascular endothelium function.
Safety,Efficacy
vascular endothelium function
Various biochemical profiles
Interventional
Parallel
Randomized
Individual
Open -but assessor(s) are blinded
Active
5
Treatment
Device,equipment |
low intensity exercise of hand grip training
moderate intensity exercise of hand grip training
high intensity exercise of hand grip training
the aerobic exercise level of walking
sedentary
20 | years-old | <= |
90 | years-old | >= |
Male and Female
1. Subjects over the age of 20 years with pre and post life style related disease
2. Subjects able to provide written informed consent for study participation
1. Patients presenting with unstable angina, acute phase acute coronary syndrome
2. Other patients deemed by a physician to be otherwise unsuitable for participation in this study
3. Subjects over the age of 90 years
65
1st name | Misa |
Middle name | |
Last name | Miura |
Tsukuba University of Technology
Faculty of health science
305-8521
4-12-7 Kasuga, Tsukuba City
029-858-9552
m.miura@k.tsukuba-tech.ac.jp
1st name | Misa |
Middle name | |
Last name | Miura |
Tsukuba University of Technology
Faculty of health science
305-8521
4-12-7 Kasuga, Tsukuba City
029-858-9552
m.miura@k.tsukuba-tech.ac.jp
Tsukuba University of Technology
Tsukuba University of Technology
Government offices of other countries
Japan
Tsukuba University of Technology
4-12-7 Kasuga, Tsukuba City
029-858-9552
m.miura@k.tsukuba-tech.ac.jp
NO
2018 | Year | 09 | Month | 14 | Day |
Partially published
file:///C:/Users/MIURA%20MISA/Downloads/364.pdf
15
No adverse events were observed due to HG exercise, and all patients were able to exercise during the study period. No significant changes in muscle strength were observed within the implementation period. There was no significant difference in vascular endothelial function; In the HD group, moderate-intensity exercise tended to improve compared to before low-intensity exercise, but high-intensity exercise tended to worsen.
2023 | Year | 09 | Month | 18 | Day |
Delay expected |
Data collection is expected to be delayed due to information collection restrictions due to the spread of the new coronavirus infection.
The subjects of this study were HD patients who had been stably undergoing maintenance dialysis for more than 3 months due to end-stage renal disease (HD group: n = 7). Healthy subjects (n=8) were used as a control group. HD patients were defined as patients who had stable blood flow for at least 3 months using an intra-forearm shunt as a blood access. Exclusion criteria are unstable angina, pulmonary hypertension, acute myocardial infarction, decrease in resting SpO2 <90%, significant decline in cognitive function, and other conditions in which the physician is inappropriate to participate in this study based on medical grounds.
The subjects of this study were 186 HD patients at a single facility who had been stably receiving maintenance dialysis for more than 3 months due to end-stage renal disease, excluding 106 patients who met the exclusion criteria. The study began with 10 patients who consented to the study, and 7 patients completed the entire protocol, excluding 3 patients who were transferred to another hospital or dropped out at their own request. For the control group, 8 of the 10 healthy volunteers who had given their consent and who had applied through posters completed the entire protocol.
There were no adverse events caused by this study.
The measurement items for this study included vascular endothelial function, arteriosclerosis measurement, grip strength, lower limb muscle strength, arteriosclerosis measurement, and various biochemical tests.
No longer recruiting
2018 | Year | 09 | Month | 13 | Day |
2017 | Year | 07 | Month | 27 | Day |
2018 | Year | 09 | Month | 13 | Day |
2022 | Year | 03 | Month | 31 | Day |
2022 | Year | 05 | Month | 30 | Day |
2023 | Year | 03 | Month | 31 | Day |
2024 | Year | 03 | Month | 31 | Day |
2018 | Year | 09 | Month | 13 | Day |
2024 | Year | 03 | Month | 18 | Day |
Value
https://center6.umin.ac.jp/cgi-open-bin/icdr_e/ctr_view.cgi?recptno=R000033251
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