Unique ID issued by UMIN | UMIN000036549 |
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Receipt number | R000039683 |
Scientific Title | risk factors for difficult postpyrolic intubation of postpyloric enteral feeding tube |
Date of disclosure of the study information | 2019/04/22 |
Last modified on | 2021/10/09 23:57:50 |
risk factors for difficult postpyrolic intubation of postpyloric enteral feeding tube
risk factors for difficult postpyrolic intubation of enteral feeding tube
risk factors for difficult postpyrolic intubation of postpyloric enteral feeding tube
risk factors for difficult postpyrolic intubation of enteral feeding tube
Japan |
patients who were inserted the post pyloric enteral feeding tube in the intensive care unit
Intensive care medicine |
Others
NO
The object is to explore the risk factors associated with the difficult insertion of the post pyloric enteral feeding tube.
Others
1) the correlation between the ICU length of stay and the number of days from tube insertion start to enteral nutrition start
2) The correlation between the ICU length of the stay and the number of days required to start enteral nutrition
The odds ratio of the risk factor related to the success rate of the enteral feeding tube insertion
Observational
20 | years-old | <= |
Not applicable |
Male and Female
Patients diagnosed as requiring the enteral nutrition
The first attempt for insertion or the replacement of the inserted enteral feeding tube
Patiants wiht gastrostomy or enterocutaneous who do not need the insetion enteral feeding tube
Patients with ileus, severe diarrhea, gastrointestinal bleeding, infection of the gastrointestinal tract
450
1st name | Masaashi |
Middle name | |
Last name | Yokose |
Yokohama city university hospital
Department of the anesthesiology and critical care medicine
2360004
3-9, Fukuura, Kanazawa-ku, Yokohama, Japan
+81457872800
yokose_p12@yahoo.co.jp
1st name | Masashi |
Middle name | |
Last name | Yokose |
Yokohama city university hospital
Department of Anesthesiology and critical care medicine
2360004
3-9, Fukuura, Kanazawa-ku, Yokohama, Japan
+81457872800
yokose_p12@yahoo.co.jp
Yokohama City University School of Medicine
Yokohama City University School of Medicine
Self funding
the institutional ethics committee of Yokohama city university hospital
3-9, Fukuura, Kanazawa-ku, Yokohama
+81457872800
rinri@yokohama-cu.ac.jp
NO
2019 | Year | 04 | Month | 22 | Day |
in preparation
Published
https://jintensivecare.biomedcentral.com/articles/10.1186/s40560-021-00577-1
455
Logistic regression analysis:
the position of the greater curvature of the stomach cephalad to L1-L2 was only associated with first pass success
odds ratio 0.62; 95% confidence interval: 0.40-0.95
2021 | Year | 10 | Month | 09 | Day |
2021 | Year | 10 | Month | 07 | Day |
Age (years) 68 (57-76)
Gender Male 265 (60) Female 177 (40)
Body mass index (kg/m2) 22.4 (19.8-24.9)
SOFA score 10 (7-13)
Diabetes mellitus, n (%) 92 (21)
Renal replacement therapy, n (%) 50 (11)
Use of cardiac assist devices, n (%) 36 (8)
Post-cardiac surgery, n (%) 180 (41)
Hematology, n (%) 43 (10)
Respiratory disease, n (%) 114 (26)
A total of 455 patients were included.
13 patients were excluded (10 patients, EFT was inserted before ICU admission; three patients, a history of upper gastrointestinal surgery)
442 patients met the inclusion criteria.
Final analysis was performed by 414 cases.
Not applicable
The first-pass success rate: 42.8% (n = 189)
The median ICU length of stay: 8 (6-14) days
VFD: 21 (6-24) days
The number of patients who died in the ICU: 35 (8%)
Logistic regression analysis for the first-pass success rate:
Variables Odds ratio 95% CI P-value
Age 0.91 0.78-1.06 0.22
Sex (female) 1.32 0.74-2.37 0.35
Height 0.91 0.68-1.23 0.55
Fluid balance (each 1-kg increment)
1.04 0.98-1.10 0.18
Serum albumin level (each 1-g/dL increment) 0.74 0.50-1.07 0.11
Position of the stomach (caudal to L1-L2
0.61 0.40-0.94 0.03
Use of sedatives
0.80 0.42-1.55 0.51
Right lateral body position
1.01 0.66-1.53 0.97
Use of prokinetic agents
1.20 0.47-3.07 0.70
Presence of intestinal peristaltic movement 0.75 0.47-1.20 0.23
Renal replacement therapy
0.52 0.26-1.05 0.07
Use of cardiac assist devices
0.86 0.39-2.01 0.77
Post-cardiovascular surgery
0.96 0.58-1.60 0.87
Completed
2018 | Year | 12 | Month | 01 | Day |
2018 | Year | 11 | Month | 21 | Day |
2019 | Year | 04 | Month | 22 | Day |
2021 | Year | 06 | Month | 30 | Day |
Predictive factors
*Factors of disease
1. SOFA (sequential organ failure assessment) Score
2. Post cardiovascular surgery
3. Respiratory disease (ARDS, pneumonia, COPD)
4. Hematologic disease (leukemia, malignant lymphoma, MDS)
*Factors of patients
5. Bowel sound level
6. BMI
7. Diabetes mellitus
8. Gastroptosis
9. Body position
10. Water balance
11. Serum Albumin
12. Age
13. Sex
*Factors of medicine
14. Use of the drug for facilitating the peristalsis
15. Use of the vasopressor
16. ECMO, IABP, LVAD
17. Renal replacement therapy
18. Experience of doctor who tries to insert
Patients characteristics data
diagnosis of disease
dose of the opioids or sedative
gastrointestinal surgery
ventilator free days at 28 days
Outcomes
The success of the initial insertion are
evaluated by the abdominal X-ray imaging immidiately after insertion.
The number of days from starting of enteral feed tube insertion to starting of enteral nutrition
The number of days from entering the ICU to starting of enteral nutrition
The ICU length of stay
Statistics analysis
The logistic regression analysis
Dependent variable: 18 predictive factors
Independent varible: success of the insertion
2019 | Year | 04 | Month | 19 | Day |
2021 | Year | 10 | Month | 09 | Day |
Value
https://center6.umin.ac.jp/cgi-open-bin/icdr_e/ctr_view.cgi?recptno=R000039683
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