Unique ID issued by UMIN | UMIN000047425 |
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Receipt number | R000054065 |
Scientific Title | Measurement of opioid sensitivity by sympathetic response evoking threshold during sevoflurane anesthesia. |
Date of disclosure of the study information | 2022/04/08 |
Last modified on | 2024/04/10 10:40:14 |
Measurement of opioid sensitivity by sympathetic response evoking threshold during sevoflurane anesthesia.
Measurement of opioid sensitivity by sympathetic response evoking threshold during sevoflurane anesthesia.
Measurement of opioid sensitivity by sympathetic response evoking threshold during sevoflurane anesthesia.
Measurement of opioid sensitivity by sympathetic response evoking threshold during sevoflurane anesthesia.
Japan |
Elective surgery patient over 20 years old
Anesthesiology |
Malignancy
NO
The validation for new index(MECK) using sympathetic response can be a indicator of the rate of change of systolic blood pressure (ROCBP) before and after skin incision during sevoflurane anesthesia
Efficacy
Correlation coefficient between MECK and ROCBP
Compare correlation coefficient between MECK and ROCBP in our previous study which used propofol with correlation coefficient of this study
Observational
20 | years-old | <= |
Not applicable |
Male and Female
Adult patients who under go open surgery which require invasive blood pressure measurement during sevoflurane anesthesia.
Patients who are informed enough and presents the will of participation to this study by written form.
Patients with irregular R-R intervals on the electrocardiogram.
Patients who cannot measure invasive blood pressure in the radial artery.
Patients with severe blood circulation or neuropathy in the upper limbs.
Patients with severe stenosis or obstructive lesions of coronary arteries and cerebrovascular disease.
Patients with contraindicated use of remifentanil or rocuronium.
30
1st name | Noboru |
Middle name | |
Last name | Saeki |
Division of Clinical Medical Science, Graduate School of Biomedical Sciences, Hiroshima University
Department of Anesthesiology and Critical Care
734-8551
1-2-3,Kasumi,Minami-ku,Hiroshima
81-082-256-5267
nsaeki@hiroshima-u.ac.jp
1st name | Daiki |
Middle name | |
Last name | Shorin |
Division of Clinical Medical Science, Graduate School of Biomedical Sciences, Hiroshima University
Department of Anesthesiology and Critical Care
734-8551
1-2-3,Kasumi,Minami-ku,Hiroshima
81-082-256-5267
dshorin@hiroshima-u.ac.jp
Department of Anesthesiology and Critical Care, Division of Clinical Medical Science, Graduate School of Biomedical Sciences, Hiroshima University
None
Self funding
Ethical Committee of Hiroshima University
1-2-3,Kasumi,Minami-ku,Hiroshima
81-082-257-5907
iryo-seisaku@office.hiroshima-u.ac.jp
NO
2022 | Year | 04 | Month | 08 | Day |
Published
30
Main results already published
2022 | Year | 02 | Month | 14 | Day |
2022 | Year | 03 | Month | 23 | Day |
2022 | Year | 04 | Month | 08 | Day |
2024 | Year | 03 | Month | 31 | Day |
Measure MECK and the rate of change of systolic blood pressure before and after skin incision under sevoflurane 0.7MAC and remifentanil 2ng/ml anesthesia.
2022 | Year | 04 | Month | 06 | Day |
2024 | Year | 04 | Month | 10 | Day |
Value
https://center6.umin.ac.jp/cgi-open-bin/icdr_e/ctr_view.cgi?recptno=R000054065
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