Unique ID issued by UMIN | UMIN000049946 |
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Receipt number | R000056886 |
Scientific Title | Right ventricular T1 mapping before and after right ventricular outflow tract reconstruction in patients with adult congenital heart disease |
Date of disclosure of the study information | 2023/01/01 |
Last modified on | 2022/12/31 12:03:15 |
Right ventricular T1 mapping before and after right ventricular outflow tract reconstruction in patients with adult congenital heart disease
Right ventricular T1 mapping before and after right ventricular outflow tract reconstruction in patients with adult congenital heart disease
Right ventricular T1 mapping before and after right ventricular outflow tract reconstruction in patients with adult congenital heart disease
Right ventricular T1 mapping before and after right ventricular outflow tract reconstruction in patients with adult congenital heart disease
Japan |
Tetralogy of Fallot
Cardiology |
Others
NO
To evaluate optimal timing of intervention for severe pulmonary regurgitation by right ventricular T1 mapping before and after right ventricular outflow tract reconstruction for severe pulmonary regurgitation in patients with Tetralogy of Fallot
Efficacy
Comparison of right ventricular Native T1 and extracellular volume fraction (ECV) before and after intervention
1) Comparison of Native T1 value of patients with adult congenital heart disease and Native T1 standard value in our institute
2) Comparison of Native T1 and ECV between surgical and catheter intervention
3) Examine the relationship between Native T1 value, ECV and each parameter
4) To examine the relationship between preoperative and postoperative Native T1 values, ECV, and cardiovascular events
Observational
15 | years-old | <= |
Not applicable |
Male and Female
Patients with adult congenital heart disease who are scheduled for right ventricular outflow tract reconstruction (including catheter intervention) aged 15 years or older
Patients who cannot undergo contrast-enhanced MRI for medical reasons are excluded.
Patients with pacemakers or implantable cardioverter-defibrillators are also excluded because they cannot be clearly imaged.
20
1st name | Naohiko |
Middle name | |
Last name | Nakanishi |
Kyoto Prefectural University of Medicine
Department of Cardiovascular Medicine
6028566
465 Kajii-cho Kawaramachi-Hirokoji, Kamigyo-ku, Kyoto 602-8566, Japan
075-251-5511
naka-nao@koto.kpu-m.ac.jp
1st name | Naohiko |
Middle name | |
Last name | Nakanishi |
Kyoto Prefectural University of Medicine
Department of Cardiovascular Medicine
6028566
465 Kajii-cho Kawaramachi-Hirokoji, Kamigyo-ku, Kyoto 602-8566, Japan
075-251-5511
naka-nao@koto.kpu-m.ac.jp
Kyoto Prefectural University of Medicine
None
Self funding
Kyoto Prefectural University of Medicine
465 Kajii-cho Kawaramachi-Hirokoji, Kamigyo-ku, Kyoto 602-8566, Japan
075-251-5337
rinri@koto.kpu-m.ac.jp
NO
2023 | Year | 01 | Month | 01 | Day |
Unpublished
Preinitiation
2022 | Year | 09 | Month | 29 | Day |
2022 | Year | 10 | Month | 04 | Day |
2023 | Year | 03 | Month | 01 | Day |
2027 | Year | 03 | Month | 31 | Day |
<Observation and examination>
1. Patient background: age, gender, medical history, comorbidities, medications, height, weight, BMI
2. Echocardiography: right ventricular area change (FAC), tricuspid annular plane systolic excursion (TAPSE), tricuspid annular systolic velocity (S'), right ventricular end diastolic volume (RVEDV (I)), right ventricular end systolic volume (RVESV (I)), right ventricular ejection fraction (RVEF), left ventricular end diastolic volume (LVEDV (I)), left ventricular end systolic volume (LVESV (I)), left ventricular ejection fraction (LVEF)
3. Contrast-enhanced MRI: RVEDV(I)/ RVESV(I), LVESV(I)/ LVEDV(I), RVEF, LVEF, cardiac output (CO), cardiac index (CI), pulmonary regurgitation fraction, Native T1 value, ECV
4. Catheterization: right atrial pressure (RAP), right ventricular pressure (RVP), pulmonary artery pressure (PAP), pulmonary wedge pressure (PCWP), aortic pressure (AoP), left ventricular pressure (LVP), CO, CI, pulmonary vascular resistance (PVR), systemic vascular resistance (SVR)
5. Laboratory tests: BNP, AST, ALT, BUN, Cre, eGFR, WBC, Hb, Plt
6. ECG: rhythm, QRS width
2022 | Year | 12 | Month | 31 | Day |
2022 | Year | 12 | Month | 31 | Day |
Value
https://center6.umin.ac.jp/cgi-open-bin/icdr_e/ctr_view.cgi?recptno=R000056886
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