UMIN-ICDS Clinical Trial
| Unique ID issued by UMIN | UMIN000050879 |
|---|---|
| Receipt number | R000057982 |
| Scientific Title | Analysis of the roles of integrin family members in lung adenocarcinoma |
| Date of disclosure of the study information | 2023/04/20 |
| Last modified on | 2023/04/18 16:38:51 |
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Basic information
Public title
Analysis of the roles of integrin family members in lung adenocarcinoma
Acronym
Analysis of the roles of integrin family members in lung adenocarcinoma
Scientific Title
Analysis of the roles of integrin family members in lung adenocarcinoma
Scientific Title:Acronym
Analysis of the roles of integrin family members in lung adenocarcinoma
Region
| Japan |
Condition
Condition
Lung adenocarcinoma
Classification by specialty
| Chest surgery |
Classification by malignancy
Malignancy
Genomic information
NO
Objectives
Narrative objectives1
The purpose of this study is to identify poor prognostic factors and to generate a prognostic prediction score through analysis of expressions and functions of integrin family members in cancer-associated fibroblasts in patients with lung adenocarcinoma
Basic objectives2
Others
Basic objectives -Others
Identify poor prognostic factors
Trial characteristics_1
Exploratory
Trial characteristics_2
Developmental phase
Not applicable
Assessment
Primary outcomes
To evaluate the expression of integrin family members in cancer-associated fibroblasts in lung adenocarcinoma tissues by immunohistochemistry, and to compare it with clinicopathological factors.
Key secondary outcomes
Base
Study type
Observational
Study design
Basic design
Randomization
Randomization unit
Blinding
Control
Stratification
Dynamic allocation
Institution consideration
Blocking
Concealment
Intervention
No. of arms
Purpose of intervention
Type of intervention
Interventions/Control_1
Interventions/Control_2
Interventions/Control_3
Interventions/Control_4
Interventions/Control_5
Interventions/Control_6
Interventions/Control_7
Interventions/Control_8
Interventions/Control_9
Interventions/Control_10
Eligibility
Age-lower limit
| 20 | years-old | <= |
Age-upper limit
| 90 | years-old | > |
Gender
Male and Female
Key inclusion criteria
The patients who underwent surgical resection of lung adenocarcinoma
Key exclusion criteria
Recurrent tumors or metastatic cancers are ruled out.
Target sample size
140
Research contact person
Name of lead principal investigator
| 1st name | Takashi |
| Middle name | |
| Last name | Suzuki |
Organization
Tohoku University
Division name
Department of Anatomic Pathology, Graduate School of Medicine
Zip code
9808575
Address
2-1 Seiryo-machi, Aoba-ku, Sendai, Miyagi, Japan.
TEL
0227178050
t-suzuki@patholo2.med.tohoku.ac.jp
Public contact
Name of contact person
| 1st name | Chihiro |
| Middle name | |
| Last name | Inoue |
Organization
Tohoku University
Division name
Department of Anatomic Pathology, Graduate School of Medicine
Zip code
980
Address
2-1 Seiryo-machi, Aoba-ku, Sendai, Miyagi, Japan.
TEL
0227178050
Homepage URL
chihiro_inoue@med.tohoku.ac.jp
Sponsor or person
Institute
Tohoku University
Institute
Department
Personal name
Chihiro Inoue
Funding Source
Organization
Self funding
Organization
Division
Category of Funding Organization
Self funding
Nationality of Funding Organization
Japan
Other related organizations
Co-sponsor
Name of secondary funder(s)
IRB Contact (For public release)
Organization
Ethics Committee Tohoku University Graduate School of Medicine
Address
2-1 Seiryo-machi, Aoba-ku, Sendai, Miyagi, Japan
Tel
022-717-8007
med-kenkyo@grp.tohoku.ac.jp
Secondary IDs
Secondary IDs
NO
Study ID_1
Org. issuing International ID_1
Study ID_2
Org. issuing International ID_2
IND to MHLW
Institutions
Institutions
Other administrative information
Date of disclosure of the study information
| 2023 | Year | 04 | Month | 20 | Day |
Related information
URL releasing protocol
Publication of results
Unpublished
Result
URL related to results and publications
Number of participants that the trial has enrolled
Results
Results date posted
Results Delayed
Results Delay Reason
Date of the first journal publication of results
Baseline Characteristics
Participant flow
Adverse events
Outcome measures
Plan to share IPD
IPD sharing Plan description
Progress
Recruitment status
Enrolling by invitation
Date of protocol fixation
| 2023 | Year | 02 | Month | 01 | Day |
Date of IRB
| 2023 | Year | 03 | Month | 01 | Day |
Anticipated trial start date
| 2023 | Year | 04 | Month | 01 | Day |
Last follow-up date
| 2025 | Year | 03 | Month | 31 | Day |
Date of closure to data entry
Date trial data considered complete
Date analysis concluded
Other
Other related information
This study is an observational study using specimens resected for treatment.
Management information
Registered date
| 2023 | Year | 04 | Month | 18 | Day |
Last modified on
| 2023 | Year | 04 | Month | 18 | Day |
Link to view the page
Value
https://center6.umin.ac.jp/cgi-open-bin/icdr_e/ctr_view.cgi?recptno=R000057982
| Research Plan | |
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| Registered date | File name |
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| Registered date | File name |
| Research case data | |
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| Registered date | File name |
