Unique ID issued by UMIN | UMIN000051126 |
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Receipt number | R000058016 |
Scientific Title | Lenvatinib - radiofrequency ablation study |
Date of disclosure of the study information | 2023/05/23 |
Last modified on | 2023/05/22 20:55:31 |
Comparison of Lenvatinib with radiofrequency ablation and radiofrequency ablation alone with radiofrequency ablation planned hepatocellular carcinoma : randomized, prospective, multicenter trial
Lenvatinib - radiofrequency ablation study
Lenvatinib - radiofrequency ablation study
Comparison of Lenvatinib with radiofrequency ablation and radiofrequency ablation alone with radiofrequency ablation planned hepatocellular carcinoma : randomized, prospective, multicenter trial
Japan |
Hepatocellular carcinoma
Hepato-biliary-pancreatic medicine |
Malignancy
NO
To investigate the suppression of post-RFA recurrence rate and efficacy of administering Lenvatinib before RFA in hepatocellular carcinoma.
Safety,Efficacy
1. recurrence rate and Time to recurrence / progression (local/ectopic) for target lesion,
2. ablation area for target lesion
Interventional
Parallel
Randomized
Individual
Open -no one is blinded
Active
YES
NO
2
Treatment
Medicine |
Lenvatinib 8mg or 12mg daily for 2-4 weeks
RFA only
Not applicable |
90 | years-old | >= |
Male and Female
1. unresectable hepatocellular carcinoma
2. Child-Pugh score <=7
1. presence of Microvascular Invasion or extrahepatic spread
2. allergy for Lenvatinib
3. patients refuse to participate in this study
4. physician judged it inappropriate to participate in this study
60
1st name | Kento |
Middle name | |
Last name | Imajo |
SHIN-YURIGAOKA General Hospital
Gastroenterology
215-0026
255, Furusawatsuko, Asao-ku, Kawasaki city, Kanagawa prefecture
044-322-9991
kento318@yokohama-cu.ac.jp
1st name | Kento |
Middle name | |
Last name | Imajo |
SHIN-YURIGAOKA General Hospital
Gastroenterology
215-0026
255, Furusawatsuko, Asao-ku, Kawasaki city, Kanagawa prefecture
044-322-9991
tera@m-kanazawa.jp
SHIN-YURIGAOKA General Hospital
Self funding
Self funding
Certified Review Board, SHIN-YURIGAOKA General Hospital
255, Furusawatsuko, Asao-ku, Kawasaki city, Kanagawa prefecture
044-322-9991
tadashi.kanbe@mt.strins.or.jp
NO
2023 | Year | 05 | Month | 23 | Day |
Unpublished
Enrolling by invitation
2023 | Year | 03 | Month | 02 | Day |
2023 | Year | 03 | Month | 27 | Day |
2023 | Year | 05 | Month | 12 | Day |
2024 | Year | 03 | Month | 31 | Day |
2023 | Year | 05 | Month | 22 | Day |
2023 | Year | 05 | Month | 22 | Day |
Value
https://center6.umin.ac.jp/cgi-open-bin/icdr_e/ctr_view.cgi?recptno=R000058016
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