Unique ID issued by UMIN | UMIN000051808 |
---|---|
Receipt number | R000059122 |
Scientific Title | Efficacy of combined antipsychotic and antihistamine therapy in cancer patients with delirium: a systematic review |
Date of disclosure of the study information | 2023/08/03 |
Last modified on | 2023/09/01 11:34:59 |
Efficacy of antipsychotics and antihistamines on delirium: a systematic review
Efficacy of antipsychotics and antihistamines on delirium: a systematic review
Efficacy of combined antipsychotic and antihistamine therapy in cancer patients with delirium: a systematic review
Efficacy of combined antipsychotic and antihistamine therapy: a systematic review
Japan |
Cancer
Hematology and clinical oncology | Psychiatry |
Malignancy
NO
To determine the efficacy of combined antipsychotic and antihistamine therapy in cancer patients with delirium
Efficacy
Change in severity of delirium before and after treatment initiation
somnolence, extrapyramidal signs and QT prolongation
Others,meta-analysis etc
18 | years-old | <= |
Not applicable |
Male and Female
1.Patients with cancer(more than or equal to 80%)
2.Patients with delirium
3.Trials including combined antipsychotic and antihistamine therapy
The study design to be considered for inclusion is as follows:
1.If there were at least two randomized controlled trial (RCT)s, inclusion was completed.
2.If there were less than 2 RCTs, we included non-RCTs or observational studies with control groups.
3.If there were no RCTs/non-RCTs/observational studies with control groups, single-arm observational studies were considered for inclusion.
1.Duplicate publications
2.Conference proceedings
1st name | Tetsuya |
Middle name | |
Last name | Ito |
IMSUT Hospital, the Institute of Medical Science, The University of Tokyo
Department of Palliative Medicine and Advanced Clinical Oncology
108-8639
4-6-1 Sirokanedai, Minato-ku, Tokyo, Japan
03-3443-8111
rachmaninov0531@gmail.com
1st name | Tetsuya |
Middle name | |
Last name | Ito |
IMSUT Hospital, the Institute of Medical Science, The University of Tokyo
Department of Palliative Medicine and Advanced Clinical Oncology
108-8639
4-6-1 Sirokanedai, Minato-ku, Tokyo, Japan
03-3443-8111
rachmaninov0531@gmail.com
IMSUT Hospital, the Institute of Medical Science, The University of Tokyo
None
Self funding
N/A
N/A
N/A
N/A
NO
2023 | Year | 08 | Month | 03 | Day |
Unpublished
Preinitiation
2023 | Year | 07 | Month | 31 | Day |
2023 | Year | 09 | Month | 01 | Day |
2024 | Year | 08 | Month | 31 | Day |
Data sources and search strategy
We will conduct a systematic review of clinical trials investigating the efficacy of combined antipsychotic and antihistamine therapy in cancer patients with delirium. This systematic review will search the following four databases: the Ichushi-Web of the Japan Medical Abstracts Society ver.5, Cochrane Library, EMBASE and MEDLINE, on 31 AUGUST, 2023. The search will include all relevant terms such as "Delirium," "Antipsychotics*," and "Antihistamine*".
Selection of studies and Assessment of risk of bias in included studies
Two review authors will independently check to ensure that studies meet the inclusion criteria. Two review authors will independently assess trial quality according to the Minds 2020 manual. If the raters disagree, the final rating will be made by consensus with the involvement, if necessary, of another review author.
2023 | Year | 08 | Month | 03 | Day |
2023 | Year | 09 | Month | 01 | Day |
Value
https://center6.umin.ac.jp/cgi-open-bin/icdr_e/ctr_view.cgi?recptno=R000059122
Research Plan | |
---|---|
Registered date | File name |
Research case data specifications | |
---|---|
Registered date | File name |
Research case data | |
---|---|
Registered date | File name |