Unique ID issued by UMIN | UMIN000052425 |
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Receipt number | R000059738 |
Scientific Title | Comparison of plasma rocuronium concentration at recovery of muscle contraction between elderly and young persons under anesthesia: exploratory observational study |
Date of disclosure of the study information | 2023/10/10 |
Last modified on | 2023/10/05 15:38:55 |
Comparison of plasma rocuronium concentration at recovery of muscle contraction between elderly and young persons under anesthesia: exploratory observational study
Comparison of plasma rocuronium concentration at recovery of muscle contraction between elderly and young persons under anesthesia: exploratory observational study
Comparison of plasma rocuronium concentration at recovery of muscle contraction between elderly and young persons under anesthesia: exploratory observational study
Comparison of plasma rocuronium concentration at recovery of muscle contraction between elderly and young persons under anesthesia: exploratory observational study
Japan |
patient undergoing elective surgery under general anesthesia
Anesthesiology |
Others
NO
The purpose of this study is to verify the hypothesis that blood rocuronium levels in the same muscle relaxation state are lower in the elderly than in the young.
PK,PD
plasma rocuronium concentration
electrolytic concentration
Observational
20 | years-old | <= |
Not applicable |
Male and Female
Patients who undergo operations under general anesthesia
Patient with allergy of rocuronium, propofol and sugammadex
Patients undergoing surgery which intraoperative administration of muscle relaxants or muscle relaxant antagonists is undesirable
Patients using drugs that affect muscle relaxants or muscle relaxant antagonists (e.g. anticonvulsants, female hormone preparations)
40
1st name | Sumire |
Middle name | |
Last name | Yokota |
Graduate School of Medicine, Chiba University
Department of Anesthesiology
260-8677
1-8-1 Inohana, Chuo-ku, Chiba city, Chiba, Japan
043-222-7171
sumirey0913@gmail.com
1st name | Sumire |
Middle name | |
Last name | Yokota |
Graduate School of Medicine, Chiba University
Department of Anesthesiology
260-8677
1-8-1 Inohana, Chuo-ku, Chiba city, Chiba, Japan
043-222-7171
sumirey0913@gmail.com
Chiba University
Others
Self funding
Graduate School of Medicine, Chiba University
1-8-1 Inohana, Chuo-ku, Chiba city, Chiba, Japan
0432227171
sumirey0913@gmail.com
NO
2023 | Year | 10 | Month | 10 | Day |
Unpublished
Open public recruiting
2023 | Year | 06 | Month | 27 | Day |
2023 | Year | 06 | Month | 27 | Day |
2023 | Year | 06 | Month | 27 | Day |
2025 | Year | 09 | Month | 30 | Day |
Method; prospective intergroup comparative study
Subjects; Patients who underwent surgery under general anaesthesia at Chiba University Hospital between October 2023 and September 2025, who met the selection criteria and consented to the study.
young persons; Between 20 and 50 years of age, elderly persons; 75 years and over.
Measurements; blood rocuronium concentration, electrolytes
2023 | Year | 10 | Month | 05 | Day |
2023 | Year | 10 | Month | 05 | Day |
Value
https://center6.umin.ac.jp/cgi-open-bin/icdr_e/ctr_view.cgi?recptno=R000059738
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